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标题: 武汉2019.9-2019.12 血液检查结果 [打印本页]
作者: indy    时间: 2022-6-12 07:28
标题: 武汉2019.9-2019.12 血液检查结果
https://mobile.twitter.com/angie ... rsation_id=20027460


This goes out to all the skeptics who think the pandemic must have started prior to late Nov-early Dec 2019.

ZERO of >40K samples in Wuhan had neutralizing antibodies in 2019. Thus SARS-CoV-2 was not spreading widely until 2020, consistent with an origin timeline in late 2019.


武汉2019.9-2019.12 血液检查结果

漂亮国对这个期间的血液是拒绝作出检查

作者: indy    时间: 2022-6-12 07:29
https://academic.oup.com/protein ... cel/pwac013/6591304
作者: indy    时间: 2022-6-12 07:34
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[size=1.0625]ACCEPTED MANUSCRIPT
Serosurvey for SARS-CoV-2 among blood donors in Wuhan, China from September to December 2019
[url=]Le Chang[/url], [url=]Lei Zhao[/url], [url=]Yan Xiao[/url], [url=]Tingting Xu[/url], [url=]Lan Chen[/url], [url=]Yan Cai[/url], [url=]Xiaojing Dong[/url], [url=]Conghui Wang[/url], [url=]Xia Xiao[/url], [url=]Lili Ren[/url] ... Show more
[url=]Author Notes[/url]


Protein & Cell, pwac013, https://doi.org/10.1093/procel/pwac013

Published:
24 May 2022

[url=]Article history[size=0.5][/url]







Abstract
The emerging of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused COVID-19 pandemic. The first case of COVID-19 was reported at early December in 2019 in Wuhan city, China. To examine specific antibodies against SARS-CoV-2 in biological samples before December 2019 would give clues when the epidemic of SARS-CoV-2 might start to circulate in populations. We obtained all 88,517 plasmas from 76,844 blood donors in Wuhan between 1st September and 31st December 2019. We first evaluated the pan-immunoglobin (pan-Ig) against SARS-CoV-2 in 43,850 samples from 32,484 blood donors with suitable sample quality and enough volume. 264 samples from 213 donors were pan-Ig reactive, then further tested IgG and IgM, and validated by neutralizing antibodies against SARS-CoV-2. 213 samples (from 175 donors) were only pan-Ig reactive, 8 (from 4 donors) were pan-Ig and IgG reactive and 43 (from 34 donors) were pan-Ig and IgM reactive. Microneutralization assay showed all negative results. In addition, 213 screened reactive donors were analyzed and didn’t show obviously temporal or regional tendency, but the distribution of age showed a difference compared with all tested donors. Then we reviewed SARS-CoV-2 antibody results from these donors who donated several times from September 2019 to June 2020, partly tested in a previous published study, no one was found a significant increase in S/CO of antibodies against SARS-CoV-2. Our findings showed no SARS-CoV-2 specific antibodies existing among blood donors in Wuhan, China before 2020, indicating no evidence of transmission of COVID-19 before December 2019 in Wuhan, China.
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Research article

[size=1.0625] Accepted manuscripts
[size=0.9375]Accepted manuscripts are PDF versions of the author’s final manuscript, as accepted for publication by the journal but prior to copyediting or typesetting. They can be cited using the author(s), article title, journal title, year of online publication, and DOI. They will be replaced by the final typeset articles, which may therefore contain changes. The DOI will remain the same throughout.



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These authors contributed equally to this article.


©The Author(s) 2022. Published by Oxford University Press on behalf of Higher Education Press.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.








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作者: 老财迷    时间: 2022-6-12 18:14
indy 发表于 2022-6-12 07:34
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比较奇怪这个结果，为何到现在才发布？
作者: indy    时间: 2022-6-12 22:07
老财迷 发表于 2022-6-12 05:14
比较奇怪这个结果，为何到现在才发布？

不知道啊，这是正规刊物的研究论文，非正式非官方的类似数据早就披露过，不过如记录标题所言而已--------信者恒信，不信者恒不信



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